Comment by cjbgkagh

If you want investors then incorporate in the US, as the cheapest money by far is in the US and they prefer to invest locally. If that’s how your funding the company then it’s probably the dominate concern.

It really depends on how you want to grow. If you’re bootstrapping on profits then tax implications can become very important. You can have a subsidiary in ‘non shady’ jurisdictions for any squeamish customers.