Comment by EMCymatics

They have already done optogenetics on non-human primates.

https://www.frontiersin.org/articles/10.3389/fnana.2023.1193...

However, I think those methods of triggering opsins are rather invasive (implants). I don't think it would be hard to design light activated opsins to recieve frequencies in the optical window of skin/bone. If I remember correctly the human body is somewhat resistant genetic transfection, so we have that going for us, which is great.

There is an optical window for skin in the near infrared band.

https://en.wikipedia.org/wiki/Near-infrared_window_in_biolog...

Bone optical windows are being explored though that has some interference with water.

https://ui.adsabs.harvard.edu/abs/2016SPIE.9689E..4JS/abstra...

Better watch what you put in your body /s