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Comment by daveguy

18 hours ago

I think the distinction there is between immediate cause and root cause. Heart disease and diabetes (or complications thereof) is the immediate cause of death, but what is causing an increase in those diseases is theory at this point.

Is it not clearly obesity? Why everyone is obese is perhaps unclear (although portion sizes, ultra processed foods, screen time and sedentary lives, etc, all seem to likely play a clear role), but I’d be surprised if the level of obesity that exists didn’t cause more heart disease and diabetes.

  • Yes. Why is everyone tiptoeing around this? The obesity rate has increased by something like 50% since the turn of the century. It is a major risk factor for all the causes of death being discussed here. Sure there are probably many factors but this is clearly a big one.

    • Go here https://www.cdc.gov/bmi/adult-calculator/index.html and enter your height and weight. If you fall above the healthy category, you are part of the obesity rate and are what most research points to when it comes to increased cardiovascular risk. Also for asians the numbers are slightly lower.

      I find that when I point this out, people often get mad. They feel they aren't obese. But the research doesn't support them, if you are anywhere outside of the "healthy" categorization you are at the same risk (that we know of so far) as "clinically obese" people.

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    • Yeah if I try to handwave obesity impact on diabetes and cardiovascular diseases to the average cardiologist, they are going to tear me a new one within minutes.

      I don't know why is this even a question. Do people really think being overweight is a net positive?

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  • I am on track to lose about 40lbs in 2024 and I suspect the main variable is really as simple as we have mastered the art of making really incredible tasting food.

    It is so pervasive though it is hard to tell until you go on a really boring and restrictive diet. It is just hard to not gain weight on average when the food tastes this good with such incredible variety.

    That is even if you buy something at the store. With our "foodie" culture, restaurants are an entire other level of choice and taste on top of that.

    • I don’t think the taste itself is an issue, it’s the availability. If I have to cook a delicious steak every time I want to eat I’m not going to randomly snack all day since it’s quite a process. My food consumption will remain at a reasonable amount. Whereas if I just pull out a bag of $chips from the pantry I could eat the whole bag without feeling sated.

    • I hope this isn't a throwaway account(!). This is a good post. Can you share what/why it is working for you? The best stories always share small experiments that people tried where they learned what didn't work.

  • Kind of. The tricky thing here is that most people have a rigid view of "obesity" in their minds as it's easier to shift blame to, but the only thing research has shown is that abnormal BMI leads to increased cardiovascular issues. Which includes slightly overweight people.

    • Higher levels of body fat (which is almost always the cause of a high BMI unless you are an active athlete) is pretty directly tied to inflammation and pre-diabetic insulin resistance. This subsequently results in the liver producing more triglycerides and lipoproteins that clog the circulatory system and the inflammation itself promotes hypertension. All of this together results in more heart attacks and strokes. There's a pretty clear mechanistic link between obesity and cardiovascular disease.

      That doesn't mean obese people are "to blame" for any medical complications they might suffer from obesity. It also doesn't mean that obesity is a death sentence; people's bodies function differently and we've all heard stories of pack a day smokers that lived into their 90s. But there is absolutely a connection between the two.

  • All those things you mention are almost certainly contributors. Another one for you to investigate if you'd like to get pissed off: endocrine-disrupting chemicals. They are everywhere and many of them are strongly tied to metabolic disorders including obesity.