Comment by scarby2
14 hours ago
I'm thinking that ozempic and zepbound will have something to say about this. When ozempic becomes available as a generic (2032) it's going to be available for $10 a dose and a huge amount of people will be taking it.
14 hours ago
I'm thinking that ozempic and zepbound will have something to say about this. When ozempic becomes available as a generic (2032) it's going to be available for $10 a dose and a huge amount of people will be taking it.
I'm not quite sure this will address the root issues. Obesity is linked with very unhealthy diet. Ozempic isn't going to address that.
It does at least potentially address that.
Ozempic's mechanism of action is not "ramp up your metabolism" or "make you absorb fewer calories from food." It's "make the desire to eat less intense, making it easier to remain on a diet plan." That diet plan could be, "eat exactly the same things but less of them," but it will often be, "cut out unhealthy snacks" or whatever.
How do you know they don’t have side effects that would reduce max life expectancy?
Entirely possible they do - but those effects would probably manifest in some fashion earlier than actual death. We'll have at least 7 years to see if we can spot them. But, even if they do exist, they will probably be small (given we haven't found them so far), and the positive effect on life expectancy via weight loss is huge.
i.e. the benefits of the weight loss almost certainly outweigh any side effects that are likely to manifest.
People have been taking them for decades for other reasons, so if they had side effects reducing max life expectancy worse than being overweight surely we'd know by now.
have they? why are they only gaining prominence now?
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We don't, but there's also no particular reason to believe it will unless some evidence for it appears.
Similar to zero-calorie sugar substitutes, "too good to be true" isn't always the case. Sometimes new inventions really are just better.
A study by researchers from the University of British Columbia (Canada) shows a link between drugs intended for diabetics and severe gastrointestinal diseases: pancreatitis, intestinal obstruction, biliary pathologies and gastroparesis.
Only fools would convince themselves a drug has no sideeffect.
The worst is that these drugs were created for legitimate use but are now being abused by what I would call lazy fat who can't get their finger out of their arse and start eating healthy.
When there is a natural, effective and no side effects alternative, why go the medication way.
When I was at university, I made a game of spending as little as possible on food. 50p/day. Didn't realise until someone here refused to believe me, that my diet then was about 1100 kcal/day during term time. Didn't feel bad at all.
A few years after graduation, for unrelated reasons, I was on antidepressants. I massively over-ate, became obese, gained stretch marks that will likely remain for life.
There was no voice in my head telling me I was even over-eating, there was no awareness of what I was doing to myself even when I felt the weird tingle in my belly that in retrospect was the tearing flesh that has the outward sign of a stretch mark — I ate without thought.
There is no "natural, effective" solution, because our natural instincts are at odds with our unnatural world.
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We don’t know if MMR doesn’t but we still give kids[0] the vaccine in infancy. The vaccine is too young (<60 y old). So I suppose ask yourself what proof you need and why.
0: most kids, I just got the disease instead and the vax later
We do know MMRV causes more seizures in kids than MMR and countries (like Canada) still choose to administer the vaccine with riskier outcomes due to costs and the fact parents don’t like to come back for more shots.
A vaccine is very different than a hormone taken daily.
Wait, doing amphetamines for weight loss is cool again and has no drawbacks of it's own?
I don't think ozempic is amphetamines.
Honest puzzlement: how is it possible to be so underinformed when google, duckduckgo and wikipedia are right there? Are they blocked some places where hacker news isn't?
Ozempic isn’t anywhere near the amphetamine class of weight control prescriptions, where are you getting your misinformation from?
Welcome to the 80s part 2. Hope you enjoy the ride.
Ozempic et al are nothing like amphetamines. They definitely have side-effects but we have far, far more evidence that the benefits are outweighed than we did for stimulants in the 80s.
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